Key features and details | |
Cat. No. | MABL-1126 |
Name | Anti-CD8 beta mAbs |
Clone No. | AFD- YTS 156.7.7 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FC, IHC |
Species Reactivity | Mouse |
Basic Information | |
Specificity | The antibody recognises the B epitope of the mouse Lyt-3 (CD8) antigen. Has been used in CD8 subset depletion in vivo and flow cytometry studies. |
Alternative Name | Lyt-3; T-cell surface glycoprotein CD8 beta chain; Lymphocyte antigen 3; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein Lyt-3; CD8b; Cd8b; Cd8b1; Ly-3; Lyt-3; Lyt3 |
UniProt | P10300 |
Immunogen | Mouse CD8 (lyt-3). |
Application Notes | This antibody recognizes murine CD8 beta. |
Antibody First Published | Cobbold S, Martin G, Waldmann H. Monoclonal antibodies for the prevention of graft-versus-host disease and marrow graft rejection. The depletion of CD8 T cell subsets in vitro and in vivo. Transplantation. 1986 Sep;42(3):239-47. PMID:3529524 |
Note on publication | Describes the production of monoclonal antibody to lyt-3 (CD-8) and demonstrates its effectiveness in CD8 subset depletion in mice. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
