Key features and details | |
Cat. No. | MABL-1139 |
Name | Anti-CD86 mAbs |
Clone No. | AFD- 3A2 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA, FC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds human B7-2 (CD86). |
Alternative Name | B7-2; B7.2; B70; BU63; CD28LG2; FUN-1; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; CTLA-4 counter-receptor B7.2; CTLA4L; CTLA-4L |
UniProt | P42081 |
Immunogen | The original antibody was isolated by panning a Fab type Rz human antibody library against CD86 antigen. |
Application Notes | This antibody can be used for detection of human B7-2 expressed on Raji B cells by flow cytometry. This antibody can be used for the detection of CD86 in an ELISA. This antibody showed inhibitory effect on T cell activity when used alone or in combination with anti-CD80 antibody 2F11 in an in vitro cell base assay. The use of combination of 3A2 and 2F11 resulted in better inhibition of T cell activity (WO2017105091). |
Antibody First Published | WO2017105091 |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
