Key features and details | |
Cat. No. | MABL-1186 |
Name | Anti-cFos mAbs |
Clone No. | AFD- C2-82 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, ELISA, IF, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for proto-oncogene c-Fos. cFos is a nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. |
Alternative Name | Proto-oncogene c-Fos; FOS; Cellular oncogene fos; G0/G1 switch regulatory protein 7 |
UniProt | P01100 |
Immunogen | This antibody was generated against the proto-oncogene c-Fos. |
Application Notes | This antibody is recommended for detection and analysis of cFos by ELISA, immunofluorescence, immunohistochemistry and western blot. |
Antibody First Published | Andrews et al. A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain eLife. 2019; 8: e43322. PMID:30667360 |
Note on publication | Describes the generation of a library of recombinant monoclonal antibodies (R- mAbs) from a pool of mAb-producing hybridomas for neuroscience research. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |