Key features and details | |
Cat. No. | MABL-1235 |
Name | Anti-collagen I mAbs |
Clone No. | AFD- AFA |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Blocking |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for the C-terminal telopeptide region of human collagen I. |
Alternative Name | CTTR1; anti-fibrotic antibody; Collagen alpha-1(I) chain; Alpha-1 type I collagen |
UniProt | P02452 |
Immunogen | The original antibody was generated by immunizing mice with α2Ct. |
Application Notes | The original antibody could block the binding activity of the C-terminal telopeptide region of human collagen I. Biosensor assays of binding interactions of the original format and the Fab fragment of the antibody with procollagen I and the α2Ct were measured (Kd = 663pM for the original antibody and 268nM for the Fab fragment and 21pM for the original antibody and 57nM for the Fab fragment for procollagen and α2Ct respectively) (US20200048333A1). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
