Anti-Cystatin C mAbs

Cat. No.

MABL-1317

Name

Anti-Cystatin C mAbs

Clone No.

AFD-AbAbNb01-CysC

From

Recombinant Antibody

Isotype

Engineer antibody

Application

ELISA

Species Reactivity

Human

Basic Information

Specificity

This antibody binds human cystatin   C. This protein acts as an inhibitor of cysteine proteinases found in a   variety of biological human fluids and secretions and acts as a regulator for   its enzymatic activity. A mutation in the gene expressing cystatin C has been   associated with amyloid angiopathy. This protein is secreted by all nucleated   cells and is freely filtered by the glomerulus. Therefore, serum concentration of cystatin C has shown great clinical potential as a biomarker   of acute kidney injury or to access renal function. Expression of this   protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role as a marker in vascular disease evaluation.

Alternative Name

CysC; Cys C; CST3; Cystatin-C; Cystatin-3; Gamma-trace; Neuroendocrine basic polypeptide;   Post-gamma-globulin; cysteine protease inhibitor C

UniProt

P01034

Immunogen

The original antibody was generated   by immunizing a Xinjiang dromedary camel with recombinant human cystatin C.   The antibody was isolated from an immune nanobody library generated from the   peripheral blood of the immunized camel after panning against human cystatin C.

Application Notes

The binding reactivity of this antibody for human cystatin C was determined using ELISA. This antibody can   be used for the analysis of serum concentration of cystatin C (CN103408667).

Antibody First Published

Note on publication

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.