Key features and details | |
Cat. No. | MABL-1370 |
Name | Anti-Desmin mAbs |
Clone No. | AFD- 14G1C12 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, ELISA, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for Desim. Desim is a muscle-specific type III intermediate filament essential for proper muscular structure and function. It plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity. |
Alternative Name | |
UniProt | P17661 |
Immunogen | The original antibody was generated by immunizing BALB/c mice with recombinant DESMIN. |
Application Notes | This antibody was used for immunohistochemistry on esophageal, leiomyoma and rhabdomyosarcoma tissue (CN109485724). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
