Key features and details | |
Cat. No. | MABL-1570 |
Name | Anti-FcRn mAbs |
Clone No. | AFD- HL161-11G |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | SPR, FC |
Species Reactivity | Rat, Human, Cynomolgus Monkey, Mouse |
Basic Information | |
Specificity | This antibody is specific for the FcRn antigen. |
Alternative Name | IgG receptor FcRn large subunit p51; FCGRT; IgG Fc fragment receptor transporter alpha chain; Neonatal Fc receptor |
UniProt | P55899 |
Immunogen | This antibody was isolated from a human single chain Fv (scFv) phage library using phage display technology. |
Application Notes | Surface plasmon resonance was performed to determine how strongly this antibody binds to soluble hFcRn (KR20130071961). Flow cytometery was performed on HEK293 cells expressing human FcRn, 3T3-L1 cells stably expressing mouse FcRn, Rat-2, a rat fibroblast stably expressing rat FcRn and Cos7 cells stably expressing monkey FcRn. The flow cytometry experiment used this antibody (KR20130071961). |
Antibody First Published | Sung Wuk et al. FcRn specific human antibody and composition for treatment of autoimmune diseases. KR20130071961 |
Note on publication | |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |