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Anti-FcRn mAbs

简要描述:

This antibody is specific for the FcRn antigen.

产品参数:

Cat. No.:MABL-1570

Species:Engineer

Species Reactivity:Rat, Human, Cynomolgus Monkey, Mouse

Type:Recombinate

Application:SPR, FC

详细介绍

Key features and   details


Cat. No.

MABL-1570

Name

Anti-FcRn mAbs

Clone No.

AFD- HL161-11G

From

Recombinant Antibody

Isotype

Engineer antibody

Application

SPR, FC

Species Reactivity

Rat, Human, Cynomolgus Monkey, Mouse

Basic Information


Specificity

This antibody is specific for the FcRn antigen.

Alternative Name

IgG receptor FcRn large subunit p51; FCGRT;   IgG Fc fragment receptor transporter alpha chain; Neonatal Fc receptor

UniProt

P55899

Immunogen

This antibody was isolated from a human   single chain Fv (scFv) phage library using phage display technology.

Application Notes

Surface plasmon resonance was performed to   determine how strongly this antibody binds to soluble hFcRn (KR20130071961). Flow cytometery was performed on HEK293 cells expressing human FcRn, 3T3-L1   cells stably expressing mouse FcRn, Rat-2, a rat fibroblast stably expressing   rat FcRn and Cos7 cells stably expressing monkey FcRn. The flow cytometry experiment used this antibody (KR20130071961).

Antibody First   Published

Sung Wuk et al. FcRn specific human antibody   and composition for treatment of autoimmune diseases. KR20130071961

Note on publication


COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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