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Anti-Galectin-4 mAbs

简要描述:

The antibody binds to human galectin-4. Galectin-4 is a protein that in humans is encoded by the LGALS4 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions.

产品参数:

Cat. No.:MABL-1648

Species:Engineer

Species Reactivity:Human

Type:Recombinate

Application:SPR, IF

详细介绍

Key features and   details


Cat. No.

MABL-1648

Name

Anti-Galectin-4 mAbs

Clone No.

AFD- FF04

From

Recombinant Antibody

Isotype

Engineer antibody

Application

SPR, IF

Species Reactivity

Human

Basic Information


Specificity

The antibody binds to human galectin-4. Galectin-4 is a protein that in humans is encoded by the LGALS4 gene. The   galectins are a family of beta-galactoside-binding proteins implicated in   modulating cell-cell and cell-matrix interactions.

Alternative Name

Gal-4; Antigen NY-CO-27; L-36   lactose-binding protein; L36LBP; Lactose- binding lectin 4

UniProt

P56470

Immunogen

The original antibody was isolated from an antibody library after three rounds of panning against human galectin-4.

Application Notes

Immunofluorescence analysis on the human colorectal adenocarcinoma cell line LS174T was performed in order to verify  the ability of the scFv fragment to recognize the natively expressed   galectin-4 antigen. The antibody showed strong cytoplasmic staining. The   binding affinity of the scFv fragment to human Galectin-4 was measured by   surface plasmon resonance (Kd= 2.44×10-7 M) (US20190309060).

Antibody First   Published


Note on publication


COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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