Key features and details | |
Cat. No. | MABL-1684 |
Name | Anti-gH mAbs |
Clone No. | AFD- 302-1G9 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | in vitro, neutralizing, ELISA |
Species Reactivity | varicella zoster virus |
Basic Information | |
Specificity | The original antibody is specific for the gH of varicella-zoster virus. |
Alternative Name | VZV; Envelope glycoprotein H |
UniProt | Q775J3 |
Immunogen | The original antibody was generated by vaccinating seven subjects (60 to 71 years old) with Zostavax. |
Application Notes | The specificity of the original format of the antibody was confirmed by ELISA analysis. The original format of the antibody was able to neutralize VZV in vitro (IC50 = 0.06 and 0.09 µg/ml with or without complement). The original format of the antibody could inhibit cell-to-cell spread in vitro (Sullivan et al., 2018; PMID： 29743372). |
Antibody First Published | Sullivan et al. Breadth and Functionality of Varicella-Zoster Virus Glycoprotein-Specific Antibodies Identified after Zostavax Vaccination in Humans. J Virol. 2018 Jun 29;92(14)：e00269-18. doi： 10.1128/JVI.00269-18. Print 2018 Jul 15. PMID：29743372 |
Note on publication | The original paper describes the generation and characterization of the antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
