Anti-H3N2 antigen from influenza A virus mAbs

Cat. No.

MABL-1764

Name

Anti-H3N2 antigen from   influenza A virus mAbs

Clone No.

AFD- IF1A11

From

Recombinant Antibody

Isotype

Engineer antibody

Application

Blocking, WB, ELISA

Species Reactivity

Influenza A

Basic Information

Specificity

The antibody binds to Influenza A H3N2 with   a Kd of 3.6 nM.

Alternative Name

Hemagglutinin; HA

UniProt

P03437

Immunogen

RNA from peripheral blood lymphocytes of a   healthy volunteer who had recovered from an Influenza A virus infection.

Application Notes

The antibody binds to H3N2, which binds to sialic acid-containing receptor on the host cell surface leading to   attachment and internalization of the virion. The antibody neutralizes the   H3N2- receptor interaction.

Antibody First   Published

Shibuya et al. Identification of a human   monoclonal Fab with neutralizing activity against H3N2 influenza A strain   from a newly constrctued human Fab library. Microbiology and Immunology 2008;   52(3):162-170 PMID:18402598

Note on publication

Describes the generation of a Fab library   and a H3N2-neutralizing antibody.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.