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Anti-hCG subunit beta mAbs

简要描述:

The antibody is specific for subunit beta of hCG. The antibody interacts with the loop 73B-81B of subunit beta.

产品参数:

Cat. No.:MABL-1782

Species:Engineer

Species Reactivity:Human

Type:Recombinate

Application:Cristallization

详细介绍

Key features and   details


Cat. No.

MABL-1782

Name

Anti-hCG subunit beta mAbs

Clone No.

AFD- Fv3468

From

Recombinant Antibody

Isotype

Engineer antibody

Application

Cristallization

Species Reactivity

Human

Basic Information


Specificity

The antibody is specific for subunit beta of   hCG. The antibody interacts with the loop 73B-81B of subunit beta.

Alternative Name

hCG; CGB; Human chorionic gonadotropin;  Choriogonadotropin subunit beta; Chorionic gonadotropin chain beta; CG-beta

UniProt

P0DN86

Immunogen

The scFv fragment was derived from hybridoma   cells secreting the monoclonal antibody designated 3468.

Application Notes

The crystal structure of the antibody in   complex with hCG subunit beta was determined (Tegoni et al., 1999; PMID:   10373373).

Antibody First   Published

Tegoni et al. Crystal structure of a ternary   complex between human chorionic gonadotropin (hCG) and two Fv fragments  specific for the alpha and beta-subunits. J Mol Biol. 1999 Jun   25;289(5):1375-85. PMID:10373373

Note on publication

The original paper describes the generation   and characterization of the antibody.

COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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