Key features and details | |
Cat. No. | MABL-1782 |
Name | Anti-hCG subunit beta mAbs |
Clone No. | AFD- Fv3468 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Cristallization |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for subunit beta of hCG. The antibody interacts with the loop 73B-81B of subunit beta. |
Alternative Name | hCG; CGB; Human chorionic gonadotropin; Choriogonadotropin subunit beta; Chorionic gonadotropin chain beta; CG-beta |
UniProt | P0DN86 |
Immunogen | The scFv fragment was derived from hybridoma cells secreting the monoclonal antibody designated 3468. |
Application Notes | The crystal structure of the antibody in complex with hCG subunit beta was determined (Tegoni et al., 1999; PMID: 10373373). |
Antibody First Published | Tegoni et al. Crystal structure of a ternary complex between human chorionic gonadotropin (hCG) and two Fv fragments specific for the alpha and beta-subunits. J Mol Biol. 1999 Jun 25;289(5):1375-85. PMID:10373373 |
Note on publication | The original paper describes the generation and characterization of the antibody. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |