Anti-hCG subunit alpha mAbs

Cat. No.

MABL-1781

Name

Anti-hCG subunit alpha mAbs

Clone No.

AFD- Fv3299

From

Recombinant Antibody

Isotype

Engineer antibody

Application

Cristallization

Species Reactivity

Human

Basic Information

Specificity

The antibody is specific for subunit alpha   of hCG. The antibody interacts with the loop 14A-21A of subunit alpha.

Alternative Name

hCG; CGA; Human chorionic gonadotropin;   Choriogonadotropin subunit alpha; Chorionic gonadotropin chain alpha;   CG-alpha

UniProt

P01215

Immunogen

The scFv fragment was derived from hybridoma   cells secreting the monoclonal antibody designated 3299.

Application Notes

The crystal structure of the antibody in complex with hCG subunit alpha was determined (Tegoni et al., 1999; PMID:  10373373).

Antibody First   Published

Tegoni et al. Crystal structure of a ternary   complex between human chorionic gonadotropin (hCG) and two Fv fragments  specific for the alpha and beta-subunits. J Mol Biol. 1999 Jun   25;289(5):1375-85. PMID:1037337.3

Note on publication

The original paper describes the generation   and characterization of the antibody.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.