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Anti-HER3 mAbs

简要描述:

This antibody binds specifically to human ErBB3.

产品参数:

Cat. No.:MABL-1819

Species:Engineer

Species Reactivity:Human

Type:Recombinate

Application:functional assay, SPR, ELISA

详细介绍

Key features and   details


Cat. No.

MABL-1819

Name

Anti-HER3 mAbs

Clone No.

AFD- AB#3

From

Recombinant Antibody

Isotype

Engineer antibody

Application

functional assay, SPR, ELISA

Species Reactivity

Human

Basic Information


Specificity

This antibody binds specifically to human ErBB3.

Alternative Name

ErBB3; Receptor tyrosine-protein kinase erbB-3; Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell   surface receptor HER3

UniProt

P21860

Immunogen

The original antibody was created using   phage display from a human Fab-phage library.

Application Notes

Surface plasmon resonace on the ErBB3  protein was performed with this antibody to determine the KD values   (US7846440). This antibody was used for a cell binding assay. The cells used   were MALME-3M cells (US7846440). The ability of this antibody to inhibit the   binding of ligands to ErBB3 was tested using ADRr cells (US7846440).

Antibody First   Published

Schoeberl et al. Antibodies against ErbB3   and uses thereof. US7846440

Note on publication


COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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