Key features and details | |
Cat. No. | MABL-1857 |
Name | Anti-HLA-Cw6 mAbs |
Clone No. | AFD- Cw6_4 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IP, FC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds human HLA-Cw6. This antigen-presenting major histocompatibility complex class I (MHCI) molecule has an important role in reproduction and antiviral immunity. |
Alternative Name | HLA-C; HLAC; HLA-Cw; HLA class I histocompatibility antigen C alpha chain; Human leukocyte antigen C |
UniProt | P10321 |
Immunogen | The original antibody was isolated from fully synthetic human combinatorial antibody library (HuCAL) by screening against a cell-bound human lymphocyte antigen HLA-Cw6. Cw6 stable cell line was generated by transfecting human lymphoblastoid LCL 721.221 HLA class I null cell line. |
Application Notes | The binding specificity of the scFv antibody towards human HLA-Cw6, expressed on the cell surface was done using flow cytometry. This antibody was also used for the immunoprecipitation of Cw*0602-transfected LCL721.221 cells (WO2001014558). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
