Key features and details | |
Cat. No. | MABL-1887 |
Name | Anti-HSP90 mAbs |
Clone No. | AFD- 6H8 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA, FC, IF |
Species Reactivity | Human, Mouse |
Basic Information | |
Specificity | This antibody is specific for HSP90 alpha. It binds to the epitope between amino acid 712 and 723. |
Alternative Name | HSP 86; HSP86; LAP-2; LPS-associated protein 2; Heat shock 86 kDa; Renal carcinoma antigen NY-REN-38; Heat shock protein family C member 1; Renal carcinoma antigen NY- REN-38; Heat shock protein HSP 90-alpha |
UniProt | P07900 |
Immunogen | This antibody was raised by immunizing a BALB/c mice with human recombinant HSP90 alpha. |
Application Notes | The original antibody was used for an ELISA on different epitopes of human HSP90 alpha. It showed that the epitope of this antibody is HSP90 alpha amino acids 712-723. This antibody was used for flow cytometry on DC2.4 cells. The antibody was used for immunostaining on DC2.4 cells, here it showed that the antibody was quickly internalized after binding to HSP90. This ability to internalize the antibody can also be leveraged to internalize compounds coupled to the antibody. This antibody was used in vitro, here it showed it could induce cytokine production in dendritic cells (US20110280881A1). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
