Key features and details | |
Cat. No. | MABL-2134 |
Name | Anti-Infectious bronchitis virus mAbs |
Clone No. | AFD- ZL.80 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Infectious bronchitis virus |
Basic Information | |
Specificity | This antibody binds the infectious bronchitis virus. |
Alternative Name | IBV; M41 strain |
UniProt | |
Immunogen | The original antibody was isolated from an immunized chicken library using phage display technology. |
Application Notes | The screening of this antibody for binding infectious bronchitis virus was done using indirect ELISA. This antibody is an affinity matured version of the original parent ZL.80 derived by a point mutation in the heavy chain variable region by substituting ValH108Tyr (Lin et al., 2011). |
Antibody First Published | Lin et al. Improved affinity of a chicken single-chain antibody to avian infectious bronchitis virus by site-directed mutagenesis of complementarity-determining region H3. African Journal of Biotechnology (2011); Vol. 10(79); pp. 18294-18302. |
Note on publication | Describes the generation of an affinity matured version of this antibody using site directed mutagenesis. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
