Key features and details | |
Cat. No. | MABL-2199 |
Name | Anti-Keratin 17 mAbs |
Clone No. | AFD- A4 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, ELISA, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | Binds specifically to human keratin, no observed crossreactivity. |
Alternative Name | |
UniProt | Q04695 |
Immunogen | Human keratin-17. |
Application Notes | This antibody binds to human keratin (K17), which is involved in the formation of skin appendages, growth of hair follicles, regulation of protein synthesis, and epithelial cell growth through SFN- binding and mTOR-stimulation. |
Antibody First Published | Wang et al. Cloning and characterization of antikeratin human antibodies using a semisynthetic phage antibody library. Archives in Dermatological Research 2004; 296(6):270-277 PMID:15340746 |
Note on publication | Describes the use of a semisynthetic phage antibody library to generate antibodies against human keratin. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |