Key features and details | |
Cat. No. | MABL-2241 |
Name | Anti-Latent TGF-beta1 mAbs |
Clone No. | AFD- 2F10 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA, IF, IHC |
Species Reactivity | Human, Mouse |
Basic Information | |
Specificity | This antibody is specific for an evolutionally conserved unique sequence (10 amino acids) located in LAP and mature TGF-β1 regions of latent TGF-β1 polypeptide. |
Alternative Name | LAP; latent TGF-β1; Transforming growth factor beta-1-binding protein 1; LTBP-1; Latent-transforming growth factor beta-binding protein 1; TGF-beta1-BP-1 |
UniProt | Q14766 |
Immunogen | The original antibody was raised by immunizing mice with evolutionally conserved unique sequences (10 amino acids) located in LAP and mature TGF-βΙ regions of latent TGF-βΙ polypeptide. |
Application Notes | Immunohistochemistry was performed against a cancer tissue array (including 6 HCC clones, 6 choiangiocarcinoma clones, 6 lung adenocarcinoma clones, 6 RCC clones, 5 breast cancer clones, 6 ovarian cancer clones, 2 cervix cancer clones) using this antibody (WO2018235964). Immunofluorescense was performed against a HepG2 cells using this antibody (WO2018235964). ELISA with this antibody was performed on antigen peptide and TGF- i (WO2018235964). This antibody was also used for immunostaining on colorectal cancer tissues (WO2019045086). |
Antibody First Published | Yukikazu et al. Anti-tgf-beta1 antibodies. WO2018235964 |
Note on publication | |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |