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Anti-Latent TGF-beta1 mAbs

简要描述:

This antibody is specific for an evolutionally conserved unique sequence (10 amino acids) located in LAP and mature TGF-β1 regions of latent TGF-β1 polypeptide.

产品参数:

Cat. No.:MABL-2241

Species:Engineer

Species Reactivity:Human, Mouse

Type:Recombinate

Application:ELISA, IF, IHC

详细介绍

Key features and   details


Cat. No.

MABL-2241

Name

Anti-Latent TGF-beta1 mAbs

Clone No.

AFD- 2F10

From

Recombinant Antibody

Isotype

Engineer antibody

Application

ELISA, IF, IHC

Species Reactivity

Human, Mouse

Basic Information


Specificity

This antibody is specific for an   evolutionally conserved unique sequence (10 amino acids) located in LAP and   mature TGF-β1 regions of latent TGF-β1 polypeptide.

Alternative Name

LAP; latent TGF-β1; Transforming growth   factor beta-1-binding protein 1; LTBP-1; Latent-transforming growth factor   beta-binding protein 1; TGF-beta1-BP-1

UniProt

Q14766

Immunogen

The original antibody was raised by   immunizing mice with evolutionally conserved unique sequences (10 amino   acids) located in LAP and mature TGF-βΙ regions of latent TGF-βΙ polypeptide.

Application Notes

Immunohistochemistry was performed against a   cancer tissue array (including 6 HCC clones, 6 choiangiocarcinoma clones, 6 lung adenocarcinoma clones, 6 RCC clones, 5 breast cancer clones, 6 ovarian   cancer clones, 2 cervix cancer clones) using this antibody (WO2018235964).   Immunofluorescense was performed against a HepG2 cells using this antibody   (WO2018235964). ELISA with this antibody was performed on antigen peptide and   TGF- i (WO2018235964). This antibody was also used for immunostaining on   colorectal cancer tissues (WO2019045086).

Antibody First   Published

Yukikazu et al. Anti-tgf-beta1 antibodies. WO2018235964

Note on publication


COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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