Key features and details | |
Cat. No. | MABL-2245 |
Name | Anti-Legionella surface antigen mAbs |
Clone No. | AFD- L74 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Legionella pneumophila |
Basic Information | |
Specificity | This antibody is capable of recognizing Legionella spp, which form a genus of pathogenic gram- negative bacteria. |
Alternative Name | Gram-negative bacteria; Legionella pneumophila |
UniProt | |
Immunogen | This antibody was generated by site-directed mutagenesis with an aspartic acid insertion mutation at position 101 of the antibody heavy chain of the original monoclonal antibody. |
Application Notes | This antibody is exhibits broader specificity towards Legionella serotypes. The specificity of this antibody for Legionella was confirmed using ELISA (PMID: 11292489). |
Antibody First Published | McCarthy Altering the fine specificity of an anti-Legionella single chain antibody by a single amino acid insertion. J Immunol Methods. (2001); 251(1-2):137-49. PMID:11292489 |
Note on publication | Describes the generation of this antibody with improved specificity using site directed mutagenesis. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |