Anti-LSR mAbs

Cat. No.

MABL-2282

Name

Anti-LSR mAbs

Clone No.

AFD- 8C8

From

Recombinant Antibody

Isotype

Engineer antibody

Application

neutralizing, ELISA, FC, IHC

Species Reactivity

Human

Basic Information

Specificity

This antibody binds specifically to the human LSR fusion protein.

Alternative Name

Lipolysis stimulated lipoprotein receptor

UniProt

Q86X29

Immunogen

The original antibody was raised by immunization   of 3 BALB/c mice using two peptides derived from the ECD region of the LSR   protein as follows: peptide 1: KSFCRDRIADAFSPASVD, and peptide 2:   CQDSVRTVRVVATKQGNA.

Application Notes

This antibody was analyzed by flow cytometry (FACS) using HEK293T transfected cells over expressing the various LSR proteins (US20140294765A1). ELISA using the human LSR fusion protein was performed on this antibody (US20140294765A1). Immunohistochemistry with this antibody was performed on HEK293T expressing LSR and, pRp ‘Empty Vector’  cells and full-face tissue sections of normal liver, tumour liver, breast   tumour and ovarian tumour (US20140294765A1). This antibody was used as a neutralizing antibody against tumors over expressing LSR proteins   (US20140294765A1).

Antibody First   Published

Cojocaru et al. Lsr antibodies, and uses   thereof for treatment of cancer. US20140294765

Note on publication

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.