Key features and details | |
Cat. No. | MABL-2296 |
Name | Anti-Lysozyme mAbs |
Clone No. | AFD- LZ-2 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FC, IF, IHC |
Specieseactivity | Human |
Basic Information | |
Specificity | This antibody recognizes intracellular human lysozyme/muramidase expressed by virtually all myelomonocytic cells, macrophages and their precursors. |
Alternative Name | 1,4-beta-N-acetylmuramidase C |
UniProt | P61626 |
Immunogen | The original mouse IgG1 version of this antibody was raised by immunizing mice against human lysozyme. |
Application Notes | The original mouse IgG1 clone is primarily used in analytics. On group used this antibody to sketch an immunophenotype for several leukemia patients (Perea et al., 2005; PMID: 16095690). Another group used the antibodies with immunofluorescence to inspect lysozymes withing patiens with specific granule deficiency, a rare disease (Serwas et al., 2018; PMID: 29651288). A final group used LZ-2 in combination with flow cytometry to analyze the development of bone marrow with and without myeloperoxidase (Scholz et al., 2004; PMID: 15003312) |
Antibody First Published | Lanza et al. Comparative Analysis of Different PermeabilizationMethods for the Flow Cytometry Measurementof Cytoplasmic Myeloperoxidase and Lysozymein Normal and Leukemic Cells Cytometry. 1997 Jun 15;30(3):134-44 PMID:9222099 |
Note on publication | Describes the usuage of an antibody in the same group as LZ-2 |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
