Key features and details | |
Cat. No. | MABL-2316 |
Name | Anti-MAdCAM-1 mAbs |
Clone No. | AFD- MECA-367 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IP, WP, Block, FC, IHC |
Species Reactivity | Mouse |
Basic Information | |
Specificity | This antibody binds to mouse MAdCAM-1, a mucosal vascular addressin. |
Alternative Name | Addressin; mucosal vascular addressin cell adhesion molecule 1 |
UniProt | |
Immunogen | Endothelial cells isolated from BALB/c mouse mesenteric and peripheral lymph nodes |
Application Notes | This antibody binds to mouse MAdCAM-1 and can be used to block lymphocyte adhesion in vitro and in vivo. |
Antibody First Published | Streeter et al. A tissue-specific endothelial cell molecule involved in lymphocyte homing. Nature. 1988 Jan 7;331(6151):41-6. PMID:3340147 |
Note on publication | Describes the role of MAdCAM-1 in lymphocyte homing. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |