Anti-MK2-23 mAbs

Cat. No.

MABL-2377

Name

Anti-MK2-23 mAbs

Clone No.

AFD- GH1002

From

Recombinant Antibody

Isotype

Engineer antibody

Application

Block

Species Reactivity

Mouse

Basic Information

Specificity

The antibody binds to the monoclonal   antibody MK2-23 with an affinity of 25 nM.

Alternative Name

MK2-23 idiotype; anti-idiotypic monoclonal antibody MK2-23

UniProt

Immunogen

Monoclonal antibody MK2-23.

Application Notes

The antibody binds specifically to MK2-23, an   idiotypic monoclonal antibody known to induce immunity in patients with malignant melanoma.

Antibody First   Published

Ban N, Day J, Wang X, Ferrone S, McPherson   A. Crystal structure of an anti- anti-idiotype shows it to be   self-complementary. J Mol Biol. 1996 Feb 2;255(4):617-27. PMID:8568901

Note on publication

Describes the structural characterisation of   the Fab fragment of the mouse anti-anti- idiotypic monoclonal antibody   GH1002. Also describes the interaction between GH1002 and the anti- idiotypic   monoclonal antibody MK2023.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.