Key features and details | |
Cat. No. | MABL-2377 |
Name | Anti-MK2-23 mAbs |
Clone No. | AFD- GH1002 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Block |
Species Reactivity | Mouse |
Basic Information | |
Specificity | The antibody binds to the monoclonal antibody MK2-23 with an affinity of 25 nM. |
Alternative Name | MK2-23 idiotype; anti-idiotypic monoclonal antibody MK2-23 |
UniProt | |
Immunogen | Monoclonal antibody MK2-23. |
Application Notes | The antibody binds specifically to MK2-23, an idiotypic monoclonal antibody known to induce immunity in patients with malignant melanoma. |
Antibody First Published | Ban N, Day J, Wang X, Ferrone S, McPherson A. Crystal structure of an anti- anti-idiotype shows it to be self-complementary. J Mol Biol. 1996 Feb 2;255(4):617-27. PMID:8568901 |
Note on publication | Describes the structural characterisation of the Fab fragment of the mouse anti-anti- idiotypic monoclonal antibody GH1002. Also describes the interaction between GH1002 and the anti- idiotypic monoclonal antibody MK2023. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
