Key features and details | |
Cat. No. | MABL-2421 |
Name | Anti-Mucin-17 mAbs |
Clone No. | AFD- 8-B7 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | functional assay, FC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds human mucin-17, which is a membrane-bound mucin that provides protection to gut epithelial cells from carcinogenic effects of chronic inflammation. It is also indicated that mucin-17 is highly expressed in gastric cancer specimens and is a compelling target for prognosis of gastric cancer. |
Alternative Name | MUC17; MUC-17; MUC3; MUC-3; Small intestinal mucin-3 |
UniProt | Q685J3 |
Immunogen | The original antibody was generated by |
Application Notes | This antibody was used in the generation of a bispecific antibody in combination with an anti-CD3 antibody. The bispecific construct designed(US20210130465). |
Antibody First Published | |
Note on publication | |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |