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Anti-Mucin-17 mAbs

简要描述:

This antibody binds human mucin-17, which is a membrane-bound mucin that provides protection to gut epithelial cells from carcinogenic effects of chronic inflammation. It is also indicated that mucin-17 is highly expressed in gastric cancer specimens and is a compelling target for prognosis of gastric cancer.

产品参数:

Cat. No.:MABL-2421

Species:Engineer

Species Reactivity:Human

Type:Recombinate

Application:functional assay, FC

详细介绍

Key features and   details


Cat. No.

MABL-2421

Name

Anti-Mucin-17 mAbs

Clone No.

AFD- 8-B7

From

Recombinant Antibody

Isotype

Engineer antibody

Application

functional assay, FC

Species Reactivity

Human

Basic Information


Specificity

This antibody binds human mucin-17, which is   a membrane-bound mucin that provides protection to gut epithelial cells from   carcinogenic effects of chronic inflammation. It is also indicated that   mucin-17 is highly expressed in gastric cancer specimens and is a compelling   target for prognosis of gastric cancer.

Alternative Name

MUC17; MUC-17; MUC3; MUC-3; Small intestinal   mucin-3

UniProt

Q685J3

Immunogen

The original antibody was generated by

Application Notes

This antibody was used in the generation of a bispecific antibody in combination with an anti-CD3 antibody. The bispecific construct designed(US20210130465).

Antibody First   Published


Note on publication


COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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