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Anti-Mucin-17 mAbs

简要描述:

​This antibody specifically recognizes the membrane bound human and cynomolgus monkey mucin-17, which is a membrane-bound mucin that provides protection to gut epithelial cells from carcinogenic effects of chronic inflammation. It is also indicated that mucin-17 is highly expressed in gastric cancer specimens and is a compelling target for prognosis of gastric cancer.

产品参数:

Cat. No.:MABL-2422

Species:Engineer

Species Reactivity:Human, Cynomolgus Monkey

Type:Recombinate

Application:FC, IHC

详细介绍

Key features and   details


Cat. No.

MABL-2422

Name

Anti-Mucin-17 mAbs

Clone No.

AFD- AbAb-MUC17

From

Recombinant Antibody

Isotype

Engineer antibody

Application

FC, IHC

Species Reactivity

Human, Cynomolgus Monkey

Basic Information


Specificity

This antibody specifically recognizes the membrane   bound human and cynomolgus monkey mucin-17, which is a membrane-bound mucin   that provides protection to gut epithelial cells from carcinogenic effects of   chronic inflammation. It is also indicated that mucin-17 is highly expressed   in gastric cancer specimens and is a compelling target for prognosis of   gastric cancer.

Alternative Name

MUC17; MUC-17; MUC3; MUC-3; Small intestinal   mucin-3

UniProt

Q685J3

Immunogen

The original antibody was generated by immunizing   B6 mice with whole CHO cells transiently expressing huMUC17.

Application Notes

This antibody can be used for the detection   of surface bound human MUC17 using flow cytometry. This antibody is   recommended for staining formalin-fixed paraffin-embedded human and   cynomolgus monkey tissues using immunohistochemistry (WO2021188851).

Antibody First   Published


Note on publication


COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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