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Anti-Mucin-17 mAbs

简要描述:

This antibody binds human mucin-17, which is a membrane-bound mucin that provides protection to gut epithelial cells from carcinogenic effects of chronic inflammation. It is also indicated that mucin-17 is highly expressed in gastric cancer specimens and is a compelling target for prognosis of gastric cancer.

产品参数:

Cat. No.:MABL-2423

Species:Engineer

Species Reactivity:Human

Type:Recombinate

Application:ELISA, FC

详细介绍

Key features and   details


Cat. No.

MABL-2423

Name

Anti-Mucin-17 mAbs

Clone No.

AFD- MQ128

From

Recombinant Antibody

Isotype

Engineer antibody

Application

ELISA, FC

Species Reactivity

Human

Basic Information


Specificity

This antibody binds human mucin-17, which is   a membrane-bound mucin that provides protection to gut epithelial cells from   carcinogenic effects of chronic inflammation. It is also indicated that   mucin-17 is highly expressed in gastric cancer specimens and is a compelling   target for prognosis of gastric cancer.

Alternative Name

MUC17; MUC-17; MUC3; MUC-3; Small intestinal   mucin-3

UniProt

Q685J3

Immunogen

The original antibody was generated by immunizing   BALB/c and MRL/MpJUmmCrj-lpr/lpr mice with Muc17ct_mIgG2aFc fusion protein.

Application Notes

The binding specificity of this antibody for human mucin-17 was determined using ELISA. The binding of this antibody to a pancreatic cancer cell line AsPc1 was evaluated by flow cytometry   (US8546546).

Antibody First   Published


Note on publication


COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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