Key features and details | |
Cat. No. | MABL-2450 |
Name | Anti-N-acetyl-ganglioside (GM1/2/3) mAbs |
Clone No. | AFD- A3 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | Broader specificity than E1, binding strongly to GM1 and GM2, and showing moderate binding to GM3. The antibody recognises only the N-acetylneuraminic acid deratives of gangliosides; no N- glycolylneuraminic acid derivatives are recognised. |
Alternative Name | |
UniProt | |
Immunogen | The antibody was generated by injecting BALB/c mice with GM1 ganglioside incorporated into liposomes. |
Application Notes | ELISA demonstrated A3 binds strongly to GM1 and GM2, and exhibits moderate binding to GM3 (Alfonso et al, 1995). |
Antibody First Published | Alfonso et al, 1995. T Cell-Independent Cell Response to Self- Monosialogangliosides: Primary Response Monoclonal Antibodies Hybridoma. 1995 Jun;14(3):209-16 PMID:7590782 |
Note on publication | Describes the original generation of A3 and its characterisation through ELISA. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
