Anti-Streptococcus pneumoniae capsular polysaccharide serotype 6B mAbs

Cat. No.

MABL-2985

Name

Anti-Streptococcus pneumoniae capsular polysaccharide serotype 6B mAbs

Clone No.

AFD- Hyp6BM8

From

Recombinant Antibody

Isotype

Engineer antibody

Application

ELISA, FC

Species Reactivity

Streptococcus pneumoniae

Basic Information

Specificity

This S. pneumoniae serogroup 6-specific antibody binds to serogroup 6B capsular polysaccharide with an affinity of   2.44 x 10^11 M^-1.This antibody also cross-reacts with the 6A polysaccharide, with an affinity of 6.41 x 10^10 M^-1, and also reacts with serotypes 6C and   6D.

Alternative Name

CPS 6B; capsular PS 6B

UniProt

Immunogen

This antibody was raised by immunising   BALB/c mice with S. pneumoniae 6B capsular polysaccharide conjugated to   keyhole limpet hemocyanin.

Application Notes

This antibody has been used in flow   cytometric analysis as part of a panel of serogroup 6-specific mAbs to define   the serologic properties of new S. pneumoniae isolates (Oliver et al, 2013).   The ability of this antibody to bind S. pneumoniae 6B and 6A serotypes has   been characterised in ELISA analysis (Sun et al, 2001).

Antibody First   Published

Sun et al. Avidity, Potency, and   Cross-Reactivity of Monoclonal Antibodies to Pneumococcal Capsular   Polysaccharide Serotype 6B Infect Immun. 2001 Jan;69(1):336-44. PMID:11119522

Note on publication

Describes the original generation of this   antibody.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.