Key features and details | |
Cat. No. | MABL-3199 |
Name | Anti-VEGFR-3 mAbs |
Clone No. | AFD- ABDD073 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA, FC, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for VEGFR-3. |
Alternative Name | FLT-4; Vascular endothelial growth factor receptor 3; EC:2.7.10.1; Fms- like tyrosine kinase 4; Tyrosine-protein kinase receptor FLT4 |
UniProt | P35916 |
Immunogen | The original antibody was generated by immunizing BALB/C mice with VEGFR-3/Ig recombinant protein. |
Application Notes | The antibody showed neutralizing activity by ELISA analysis. The antibody detected VEGFR-3 from HEL cell lysates by western blot analysis. The antibody could recognize VEGRF-3 on fetal heart, fetal kidney and fetal lung tissue by immunohistochemistry. The binding activity of the antibody to VEGFR-3 expressed on the surface of HEL cells was confirmed by FACS flow cytometry. In vitro experiments showed the antibody could block the interaction between VEGFR-3 and VEGF-D. The antibody could inhibit HEL cell proliferation. The antibody could inhibit the generation of chicken embryo allantoic membrane blood vessels induced by recombinant GST-VEGF-D (CN1800373A). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
