Key features and details | |
Cat. No. | MABL-3217 |
Name | Anti-VISTA mAbs |
Clone No. | AFD- 11A4 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, ELISA, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for VISTA protein. VISTA is an immunoregulatory receptor which inhibits the T-cell response, which may promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. |
Alternative Name | PD-1H; V-Type Immunoglin Domain-Containing Suppressor of T- Cellactivation; Platelet receptor Gi24; Stress-induced secreted protein-1; Sisp-1; V-set domain-containing immunoregulatory receptor; V-set immunoregulatory receptor; D5L5T;CGMCCNO 20766 |
UniProt | Q9H7M9 |
Immunogen | The original antibody was generated by immunizing a mouse with the recombinant VISTA protein. |
Application Notes | The antibody 11A4 and the commercial antibody D5L5T were used to stain epithelial vascular sarcoma, placental trophoblasts and urethral carcinoma in immunohistochemistry. Results showed the antibody specificity is equivalent to the commercial antibody. Further, the staining intensity of the antibody 11A4 was higher than the commercial antibody (CN112940125A). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
