Key features and details | |
Cat. No. | MABL-3253 |
Name | Anti-YKL-40 mAbs |
Clone No. | AFD- N-AY |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Block, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds human chitinase-3-like protein 1 also known as CHI3L1 or YKL-40. This molecule lacks chitinase activity due to mutations within the active site. |
Alternative Name | CHI3L1; CGP-39; GP-39; hCGP-39; BRP39; Chitinase-3-like protein 1; 39 kDa synovial protein; Cartilage glycoprotein 3 |
UniProt | P36222 |
Immunogen | The original antibody was generated by immunizing mice with YKL-40 recombinant protein called Tyr 22-THR 383. |
Application Notes | The blocking effect of this antibody in the serum of patients with liver cancer lung metastasis was determined using ELISA. This antibody is capable of reducing the serum YKL-40 concentration in patients with lung cancer (CN112375147) |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
