Anti-730.1.4 mAbs

Cat. No.

MABL-327

Name

Anti-730.1.4 mAbs

Clone No.

AFD- 409.5.3

From

Recombinant Antibody

Isotype

Engineer antibody

Application

Block

Species Reactivity

n/a

Basic Information

Specificity

Alternative Name

733.1.4 idiotype;E2 specific feline infectious peritonitis virus-neutralizing antibody (anti-idiotype)

UniProt

Immunogen

Monoclonal antibody 730.1.4.

Application Notes

The antibody binds specifically to the   antibody 730.1.4, which neutralises feline infectious peritonitis virus   (FIPV). The FIPV virus causes a fatal disease that affects cats by its   ability to invade and grow in macrophages, which causes an inflammatory response   in the infected tissue. When injected into mice, the antibody 409.5.3 has   been shown to elicit the production of 730.1.4 antibodies, thereby indirectly   neutralising the virus.

Antibody First Published

Escobar JC, Kochik SA, Skaletsky E,   Rosenberg JS, Beardsley TR. Immunization of cats against feline infectious   peritonitis with anti-idiotypic antibodies. Viral Immunol. 1992   Spring;5(1):71-9. PMID:1319173

Note on publication

Describes the characterisation of the   anti-idiotypic monoclonal antibody 409.5.3, which is raised against an antibody that neutralises feline infectious peritonitis virus.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.