Key features and details | |
Cat. No. | MABL-528 |
Name | Anti-BmR1 mAbs |
Clone No. | AFD- Ab4 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Lymphatic filariasis |
Basic Information | |
Specificity | The antibody is specific for BmR1. |
Alternative Name | |
UniProt | |
Immunogen | The original antibody was isolated by panning a human scFv library against BmR1 antigen. |
Application Notes | The specificity of the original format of the antibody was confirmed by ELISA analysis (Rahumatullah et al., 2017; PMID:29165352). The scFv format of the antibody and the Ab4-Fc construct were tested as QC reagents in two commercial rapid test kits for the detection of BmR1. Ab4-Fc showed positive reaction with both rapid tests, while Ab4 did not show reactivity with neither of them (Rahumatullah et al., 2020; PMID: 31933469). |
Antibody First Published | Rahumatullah et al. Antibody-Based Protective Immunity against Helminth Infections Antibody Phage Display Derived Antibodies against BmR1 Antigen Int J Mol Sci. 2017 Nov 22;18(11)：2376. doi: 10.3390/ijms18112376. PMID：29165352 |
Note on publication | The original paper describes the generation and characterization of the original antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
