Key features and details | |
Cat. No. | MABL-582 |
Name | Anti-Cadherin 17 mAbs |
Clone No. | AFD- AV17.3 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Human, Mouse |
Basic Information | |
Specificity | This antibody recognizes the domain 1-2 of the human cadherin 17. This antibody also cross reacts with mouse cadherin 17. Cadherins are calcium-dependent cell adhesion proteins. It is localized on the surfaces of epithelial cells in regions of cell-cell contact known as adherens junctions. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. |
Alternative Name | Cadherin-17; CDH17; Intestinal peptide-associated transporter HPT-1; Liver-intestine cadherin; LI-cadherin |
UniProt | Q12864 |
Immunogen | The original antibody was isolated from a human single chain antibody fragments (scFv) library using phage display technology. The library was panned against domain 1-2 of human cadherin-17. |
Application Notes | The binding affinity of this antibody to human cadherin 17 was determined using ELISA. The scFv version of this antibody binds human and mouse cadherin-17 with an affinity of 8.43×10^(−7) M and 6.4×10^(−7) M respectively (US20190309060). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
