Key features and details | |
Cat. No. | MABL-583 |
Name | Anti-Cadherin 17 mAbs |
Clone No. | AFD- D2111 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | PET imaging, ELISA, FC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody recognizes the human cadherin 17. Cadherins are calcium-dependent cell adhesion proteins. It is localized on the surfaces of epithelial cells in regions of cell-cell contact known as adherens junctions. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. |
Alternative Name | Cadherin-17; CDH17; Intestinal peptide-associated transporter HPT-1; Liver-intestine cadherin; LI-cadherin |
UniProt | Q12864 |
Immunogen | The original antibody was generated by immunizing GP64 transgenic mice with human cadherin 17. |
Application Notes | The binding characterization and epitope mapping of this antibody was done using ELISA. This antibody was capable of binding Huh6 cell line (liver cancer) and AGS cells (gastric cancer) in flow cytometry. Cu64 labelled version of this antibody was also used in the PET imaging of AGS transplant mice (JP2017024991). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
