Key features and details | |
Cat. No. | MABL-596 |
Name | Anti-Calponin protein mAbs |
Clone No. | AFD- 24H5 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for calponin protein.Calponin protein is a thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. Further, the interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. |
Alternative Name | CAP; Calponin-2; Calponin H2, smooth muscle; Neutral calponin; CGMCNO 20775 |
UniProt | Q99439 |
Immunogen | The original antibody was generated by immunizing mice with Calponin protein. |
Application Notes | The antibody specifically detected Calponin beta protein in Western blot analysis. The antibody 24H5 and the commercial antibody CALP were used to stain uterine fibroids and liver tissue.Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 24H5 was higher than the commercial antibody (CN113234155A). |
Antibody First Published | |
Note on publication | |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |