Name
C2 Human
Cat. No.
MAG-5181
Tag/Conjugates
His
Source
Human Plasma.
Shipped
Shipped with Ice Packs
Description
Human Complement C2 produced in Human plasma having a molecular mass of 93 kDa.
Synonyms
Complement C2, C3/C5 convertase, C2.
Introduction
C2 forms the proteolytic subunit of the C3 and C5 convertase of both pathways. Initiation of each pathway generates proteolytic enzyme complexes which binds to the target surface. C1s and MASP in these complexes activate both C4 and C2. They cleave a peptide bond in C4 depositing C4b on the surface and also cleave C2 into 2 fragments.
Physical Appearance
Sterile Filtered solution.
Formulation
25mM sodium phosphate and 100mM NaCl, pH 6.0.
Stability
C2 Human is stable at 4°C if entire vial will be used within 2-4 weeks.Store, frozen below -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence
/
Safety Data Sheet
SDS
Usage
Mabioway's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
