Name
CFP Human, Native
Cat. No.
MAG-5220
Tag/Conjugates
His
Source
Human Plasma.
Shipped
Shipped with Ice Packs
Description
CFP Human produced in Human plasma having a molecular weight of 53kDa.
Synonyms
Properdin, Complement factor P, CFP, PFC, Complement factor properdin, BFD, PFD, Properdin.
Introduction
Complement Factor Properdin (CFP) which is a plasma glycoprotein, is a positive regulator of the alternative complement pathway of the innate immune system. CFP binds and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that eventually ends with formation of the membrane attack complex and lysis of the target cell. Mutations in CFP lead to 2 forms of properdin deficiency that cause high susceptibility to meningococcal infections.
Physical Appearance
Sterile filtered solution.
Formulation
CFP solution contains 10mM Sodium phosphate and 145mM NaCl, pH 7.3.
Stability
CFP Human is stable at 4°C if entire vial will be used within 2-4 weeks. Store, frozen below -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
/
Safety Data Sheet
SDS
Usage
Mabioway's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
