Name
EFNA3 Human
Cat. No.
MAG-5389
Tag/Conjugates
His
Source
E.coli.
Shipped
Shipped with Ice Packs
Description
EFNA3 Human Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 217 amino acids (23-214 a.a) and
having a molecular mass of 24kDa. EFNA3 is fused to a 25 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Synonyms
Ephrin-A3, EFL2, Ehk1-L, EPLG3, LERK3, EPH-related receptor tyrosine kinase ligand 3.
Introduction
EFNA3
belongs to the ephrin (EPH) family. The ephrins and EPH-related receptors include
the largest
subfamily of receptor protein-tyrosine kinases which have been implicated in
mediating developmental events , especially in the nervous system and in erythropoiesis.
Ephrins are divided into the ephrin-A (EFNA) class and the ephrin-B (EFNB)
class, based on their structures and sequence relationships. The
Ephrins from the EFNA class are anchored to the membrane by a glycosylphosphatidylinositol linkage, while
the others from the EFNB class are transmembrane proteins .
Physical Appearance
Sterile Filtered colorless solution.
Formulation
EFNA3 protein solution (1mg/ml) containing 20mM Tris-HCl
buffer (pH 8.0), 0.4M Urea and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 90% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSHM QGPGG ALGNRHAVYW NSSNQHLRRE GYTVQVNVND YLDIYCPHYN
SSGVGPGAGP GPGGGAEQYV LYMVSRNGYR TCNASQGFKR WECNRPHAPH SPIKFSEKFQ RYSAFSLGYE
FHAGHEYYYI STPTHNLHWK CLRMKVFVCC ASTSHSGEKP
VPTLPQFTMG PNVKINVLED FEGENPQVPK LEKSISG
Safety Data Sheet
SDS
Usage
Mabioway's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
