Name
ICAM5 Human
Cat. No.
MAG-5679
Tag/Conjugates
His
Source
HEK293.
Shipped
Shipped with Ice Packs
Description
ICAM5 Human Recombinant produced in HEK293 is a single, glycosylated polypeptide chain containing 1052 amino acids (23-835 a.a) and having a molecular mass of 113.8kDa. ICAM5 is fused to a 239 amino acid hIgG-His-tag at C-terminus & purified by proprietary chromatographic techniques.
Synonyms
Intercellular adhesion molecule 5, ICAM5, ICAM-5, Telencephalin, telencephalin, TLN, TLCN, TLNtelencephalin, TLCNTelencephalin.
Introduction
Intercellular Adhesion Molecule-5 or ICAM-5 is a glycoprotein, part of the immunoglobulin family and located in the cell membrane. We can find ICAM-5 in telencephalic neurons, in a couple of adhesion activity, firstly heterophilic binding amid neurons and leukocytes and secondly, homophilic binding amid neurons. ICAM-5 is expressed exclusively in telencephalic areas of the central nervous system. Similar to other ICAMs molecules, ICAM-5 adhere to LFA-1 which is a leukocyte integrin.
Physical Appearance
Sterile
filtered colorless solution.
Formulation
ICAM5 protein solution (0.5mg/ml) containing Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
LFGLSAVSQE PFWADLQPRV AFVERGGSLW LNCSTNCPRP ERGGLETSLR RNGTQRGLRW LARQLVDIRE PETQPVCFFR CARRTLQARG LIRTFQRPDR VELMPLPPWQ PVGENFTLSC RVPGAGPRAS LTLTLLRGAQ ELIRRSFAGE PPRARGAVLT ATVLARREDH GANFSCRAEL DLRPHGLGLF ENSSAPRELR TFSLSPDAPR LAAPRLLEVG SERPVSCTLD GLFPASEARV YLALGDQNLS PDVTLEGDAF VATATATASA EQEGARQLVC NVTLGGENRE TRENVTIYSF PAPLLTLSEP SVSEGQMVTV TCAAGAQALV TLEGVPAAVP GQPAQLQLNA TENDDRRSFF CDATLDVDGE TLIKNRSAEL RVLYAPRLDD SDCPRSWTWP EGPEQTLRCE ARGNPEPSVH CARSDGGAVL ALGLLGPVTR ALSGTYRCKA ANDQGEAVKD VTLTVEYAPA LDSVGCPERI TWLEGTEASL SCVAHGVPPP DVICVRSGEL GAVIEGLLRV AREHAGTYRC EATNPRGSAA KNVAVTVEYG PRFEEPSCPS NWTWVEGSGR LFSCEVDGKP QPSVKCVGSG GATEGVLLPL APPDPSPRAP RIPRVLAPGI YVCNATNRHG SVAKTVVVSA ESPPEMDEST CPSHQTWLEG AEASALACAA RGRPSPGVRC SREGIPWPEQ QRVSREDAGT YHCVATNAHG TDSRTVTVGV EYRPVVAELA ASPPGGVRPG GNFTLTCRAE AWPPAQISWR APPGALNIGL SSNNSTLSVA GAMGSHGGEY ECAATNAHGR HARRITVRVA GPW LEPKSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSRDELTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGKHHHH HH.
Safety Data Sheet
SDS
Usage
Mabioways products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
