Key features and details | |
Cat. No. | MABL-3512 |
Name | Anti-DIII domain of Dengue E protein mAbs |
Clone No. | DV10 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | NTRL, ELISA |
Species Reactivity | DengueVirus |
Basic Information | |
Specificity | This antibody specifically recognizes an epitope in the DIII domain of E protein of DENV-1, DENV-2, DENV-3 and DENV-4 serotypes. This antibody was isolated as a human IgG1 from a patient recovered from a primary DENV-2 infection and neutralises infection. |
Alternative Name | Envelope protein |
UniProt | |
Immunogen | Made by immortalizing IgG-expressing B cells Dengue Virus (DENV) patients after primary or secondary infection. |
Application Notes | |
Antibody First Published | Beltramello et al. The human immune response to Dengue Virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity. Cell Host Microbe. 2010 Sep 16;8(3):271-83. PMID:20833378 |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
