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Anti-DI/DII domain of Dengue E protein mAbs [DV18](MABL-3513)

简要描述:

This antibody specifically recognizes an epitope in the DI/DII domain of E protein of DENV-1, DENV-2, DENV-3 and DENV-4 serotypes. This antibody was isolated as a human IgG1 from a patient recovered from a secondary DENV-2 infection and neutralises infection.

产品参数:

Cat. No.:MABL-3513

Species:Engineer

Species Reactivity:DengueVirus

Type:Recombinate

Application:NTRL, ELISA

详细介绍

Key features and   details


Cat. No.

MABL-3513

Name

Anti-DI/DII domain of  Dengue E protein mAbs 

Clone No.

DV18

From

Recombinant Antibody

Isotype

Engineer antibody

Application

NTRL, ELISA

Species Reactivity

DengueVirus

Basic Information


Specificity

This antibody specifically recognizes an   epitope in the DI/DII domain of E protein of DENV-1, DENV-2, DENV-3 and   DENV-4 serotypes. This antibody was isolated as a human IgG1 from a patient   recovered from a secondary DENV-2 infection and neutralises infection.

Alternative Name

Envelope protein

UniProt


Immunogen

Made by immortalizing IgG-expressing B cells   Dengue Virus (DENV) patients after primary or secondary infection.

Application Notes


Antibody First   Published

Beltramello et al. The human immune response to Dengue Virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity. Cell Host   Microbe. 2010 Sep 16;8(3):271-83. PMID:20833378

Note on publication


COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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