Name
HGF B Human Protein
Cat. No.
MAG-2037
Tag/Conjugates
His
Source
Escherichia Coli.
Shipping
Shipped with Ice Packs
Description
HGF-B Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 234 amino acids fragment (495-728) having a molecular weight of 34kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. The HGF-B is purified by proprietary chromatographic techniques.
Synonyms
Leptin tA Rat
Introduction
Hepatocyte Growth Factor (HGF) is a multifunctional growth factor which regulates both cell growth and cell motility. It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells. HGF synergizes with Interleukin-3 and GM-CSF to stimulate colony formation of hematopoietic progenitor cells in vitro and may, therefore, also modulate hematopoiesis. HGF is secreted as a single inactive polypeptide which is cleaved by serine proteases into a 69kDa Alpha chain and 34kDa Beta chain. A disulfide bond linking the alpha and beta chains produces the active heterodimeric molecule.
Physical Appearance
Sterile Filtered clear solution.
Formulation
HGF-B protein is supplied in 25mM Na. Acetate, pH 4.8, 1mM EDTA and 50% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Biological Activity
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Amino acid sequence
VVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTAR QCFPSRDLKDYEAWLGIHDVHGRGDEKCKQVLNVSQLV YGPEGSDLVLMKLARPAVLDDFVSTIDLPNYGCTIPEKTS CSVYGWGYTGLINYDGLLRVAHLYIMGNEKCSQHHRGK VTLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMV LGVIVPGRGCAIPNRPGIFVRVAYYAKWIHKIILTYKVPQS.
Usage
Mabioway's Co., Ltd products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Background
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Solubility
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