Name
MIF Mouse Protein
Cat. No.
MAG-2132
Tag/Conjugates
His
Source
Escherichia Coli.
Shipping
Shipped with Ice Packs
Description
MIF Mouse Recombinant produced in E.Coli is a single,
non-glycosylated polypeptide chain containing 138 amino acids (1-115 a.a) and
having a molecular mass of 14.9kDa. MIF is fused to a 23 amino acid His-tag at N-terminus
& purified by proprietary chromatographic techniques.
Synonyms
Macrophage migration inhibitory factor, MIF, Delayed
early response protein 6, DER6, Glycosylation-inhibiting factor, GIF,
L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase.
Introduction
The cytokine Macrophage migration inhibitory factor (MIF) has been identified to be secreted by the pituitary gland and the monocyte/macrophage and to play an important role in endotoxic shock. MIF has the unique property of being released from macrophages and T cells in response to physiological concentrations of glucocorticoids. The secretion of MIF is tightly regulated and decreases at high, anti-inflammatory steroid concentration.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
MIF protein solution (0.5mg/ml) containing Phosphate
buffered saline , 10% glycerol
and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4
weeks.
Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier
protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater
than 90.0% as determined by SDS-PAGE.
Biological Activity
/
Amino acid sequence
MGSSHHHHHH
SSGLVPRGSH MGS MPMFIVN
TNVPRASVPE GFLSELTQQL AQATGKPAQY IAVHVVPDQL MTFSGTNDPC ALCSLHSIGK IGGAQNRNYS
KLLCGLLSDR LHISPDRVYI NYYDMNAANV GWNGSTFA.
Usage
Mabioway's Co., Ltd products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Background
/
Solubility
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