Name
IgG Human
Cat. No.
MAG-7449
Tag/Conjugates
His
Shipped
At Room Temperature
Description
Human IgG protein produced in Human plasma having a molecular mass of 150kDa.
Introduction
Immunoglobulin G (IgG) are antibody molecules. Each IgG is composed of four peptide chains - 2 heavy chains g and 2 light chains. Also, each IgG has 2 antigen binding sites. IgG antibodies are involved in primarily the secondary immune response. The presence of specific IgG, generally, relates to maturation of the antibody response. IgG also has an imperative role in Antibody-dependent cell-mediated cytotoxicity (ADCC) and Intracellular antibody-mediated proteolysis, in which it binds to TRIM21 (the receptor with greatest affinity to IgG in humans) in order to direct marked virions to the proteasome in the cytosol.
Synonyms
Ig gamma-2A chain C region, A allele, Immunoglobulin heavy chain gamma polypeptide, Ighg, Igh-1, Igh-1a, 1810060O09Rik.
Source
Human serum.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Solubility
It is recommended to reconstitute the lyophilized IgG Human in phosphate buffer pH >7.0 containing 0.15M NaCl.
Stability
IgG Human although stable at room temperature for 3 weeks, should be stored between 2-8°C.
Biological Activity
/
Safety Data Sheet
SDS
Usage
Mabioway's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Formulation
The protein was lyophilized (0.2 µm filtered) from 20mM NH 4 HCO 3 .
Purity
Greater than 96.0%.
Human Virus Test
Human Immunoglobulin-G has been tested and certified negative for antibodies to HIV-1, HIV-2, HCV and HBSAG.
