Name
IL 18 Mouse Protein
Cat. No.
MAG-1515
Tag/Conjugates
His
Source
Escherichia Coli.
Shipping
Shipped with Ice Packs
Description
IL 18 Mouse Recombinant produced in E.Coli is a single,
non-glycosylated, polypeptide chain containing 158 amino acids (36-192 a.a.)
and having a molecular mass of 18.2kDa. The IL 18 is purified by proprietary chromatographic techniques.
Synonyms
Interleukin-18, IL-18, IFN gamma-inducing factor, IFN-gamma-inducing factor, Interleukin-1 gamma, IL-1 gamma.
Introduction
IL-18 is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.
Biological Activity
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Physical Appearance
Sterile Filtered clear solution.
Formulation
The IL 18 protein solution (0.5mg/ml) contains Phosphate
Buffered Saline (pH7.4).
Solubility
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Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MNFGRLHCTT AVIRNINDQV LFVDKRQPVF EDMTDIDQSA SEPQTRLIIY
MYKDSEVRGL AVTLSVKDSK MSTLSCKNKI ISFEEMDPPE NIDDIQSDLI FFQKRVPGHN KMEFESSLYE
GHFLACQKED DAFKLILKKK DENGDKSVMF TLTNLHQS.
Usage
Mabioway's Co., Ltd products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Background
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