Name
TNFRSF8 Human Protein
Cat. No.
MAG-1825
Tag/Conjugates
His
Source
Sf9,
Baculovirus cells.
Shipping
Shipped with Ice Packs
Description
TNFRSF8 produced in Sf9 Baculovirus cells is a single,
glycosylated polypeptide chain containing 370 amino acids (19-379 a.a.) and
having a molecular mass of 39.5kDa (Migrates at 40-57kDa on SDS-PAGE under
reducing conditions). TNFRSF8 is expressed with a 9 amino acid His tag at
C-Terminus and purified by proprietary chromatographic techniques.
Synonyms
Tumor Necrosis Factor Receptor Superfamily, Member 8,
Lymphocyte Activation Antigen CD30, CD30L Receptor, Ki-1 Antigen, D1S166E,
CD30, Cytokine Receptor CD30, CD30 Antigen, Ki-1.
Introduction
Tumor necrosis factor receptor superfamily member 8 (TNFRSF8) is a receptor for TNFSF8/CD30L. TNFRSF8 has a role in the regulation of cellular growth and transformation of activated lymphoblasts. In addition, the TNFRSF8 protein regulates gene expression via activation of NF-kappa-B. TNFRSF8 being a regulator of apoptosis, induces cell death or proliferation, depending on the cell type.
Biological Activity
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Physical Appearance
Sterile Filtered colorless solution.
Formulation
TNFRSF8
protein solution (1mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10%
glycerol.
Solubility
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Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater
than 95.0% as determined by SDS-PAGE.
Amino acid sequence
ADP FPQDRPF EDTCHGNPSH YYDKAVRRCC YRCPMGLFPT QQCPQRPTDC RKQCEPDYYL DEADRCTACV TCSRDDLVEK TPCAWNSSRV CECRPGMFCS TSAVNSCARC FFHSVCPAGM IVKFPGTAQK NTVCEPASPG VSPACASPEN CKEPSSGTIP QAKPTPVSPA TSSASTMPVR GGTRLAQEAA SKLTRAPDSP SSVGRPSSDP GLSPTQPCPE GSGDCRKQCE PDYYLDEAGR CTACVSCSRD DLVEKTPCAW NSSRTCECRP GMICATSATN SCARCVPYPI CAAETVTKPQ DMAEKDTTFE APPLGTQPDC NPTPENGEAP ASTSPTQSLL VDSQASKTLP IPTSAPVALS S TGK HHHHHH .
Usage
Mabioway's Co., Ltd products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Background
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