Name
TNFSF7 Human Protein
Cat. No.
MAG-1833
Tag/Conjugates
His
Source
Sf9,
Baculovirus cells.
Shipping
Shipped with Ice Packs
Description
TNFSF7 produced in Sf9 Baculovirus cells is a single,
glycosylated polypeptide chain containing 164 amino acids (39-193 a.a.) and
having a molecular mass of 18.2kDa. TNFSF7 is expressed with a 6 amino acid His tag at
C-Terminus and purified by proprietary chromatographic techniques.
Synonyms
CD70
Molecule, Tumor Necrosis Factor (Ligand) Superfamily, Member 7, Tumor Necrosis
Factor Ligand Superfamily Member 7 , CD27 Ligand, CD27LG, TNFSF7, CD27-L,
CD27L, Tumor Necrosis Factor Ligand 8A, Surface Antigen CD70, Ki-24 Antigen,
CD70 Antigen, TNLG8A.
Introduction
CD70 also known as TNFSF7 is a cytokine which binds to CD27. TNFSF7 takes part in T-cell activation as well as induces the proliferation of costimulated T-cells. Moreover, TNFSF7 enhances the generation of cytolytic T-cells. Among the diseases which are associated with TNFSF7: Include acute myocarditis & Myocarditis.
Biological Activity
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Physical Appearance
Sterile Filtered colorless solution.
Formulation
TNFSF7
protein solution (0.25mg/ml) contains Phosphate Buffered Saline (pH 7.4) and
10% glycerol.
Solubility
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Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater
than 90.0% as determined by SDS-PAGE.
Amino acid sequence
ADP QRFAQAQ
QQLPLESLGW DVAELQLNHT GPQQDPRLYW QGGPALGRSF LHGPELDKGQ LRIHRDGIYM VHIQVTLAIC
SSTTASRHHP TTLAVGICSP ASRSISLLRL SFHQGCTIAS QRLTPLARGD TLCTNLTGTL LPSRNTDETF
FGVQWVRP HH HHHH .
Usage
Mabioway's Co., Ltd products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Background
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