Cat. No.
MABL-001
Application
WB, IHC
Isotype
Engineer antibody
Species Reactivity
Rat, Mouse
Clone No.
OX7
From
Recombinant Antibody
Specificity
Rat CD90, also known as Thy1.1, a GPI-anchored membrane protein containing a single V type Ig-like domain.
Alternative Names
CD90; Thy-1 antigen; OX-7 UniProt Accession Number of Target Protein
UniProt
P01830
Immunogen
Rat Thy- 1L+ antigen in complete Freund's adjuvant.
Application Notes
This antibody binds to Thy1.1, which is allelically restricted between different host strains. Administration of OX7 leads to anti-Thy1 Glomerulonephritis.
Antibody First Published
Mason DW, Williams AF. The kinetics of antibody binding to membrane antigens in solution and at the cell surface. Biochem J. 1980 Apr 1;187(1):1-20. PMID:6967725
Note on publication
Describes the generation of the antibody, shows it recognised Thy1.1 (Thy-1) by immuno-blotting of cell lines including thymocytes, neuronal cells, stem cells, immature B cells and connective tissues.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
