Cat. No.
MABL-078
Application
IB, IP, IHC
Isotype
Engineer antibody
Species Reactivity
Rat, Human, Mouse
Clone No.
K66/38
From
Recombinant Antibody
Specificity
This antibody is specific for KChIP3. It does not react with KChIP1, KChIP2 or KChIP4.
Alternative Names
K66/38R; Kv channel-interacting protein 3; Kcnip3, A-type potassium channel modulatory protein 3; Calsenilin; Csen; DRE- antagonist modulator; Dream
UniProt
Q9JM47
Immunogen
This antibody was raised by immunising BALB/c mice with a fusion protein containing full- length rat KChIP3.
Application Notes
This antibody has been used in immunoblot analysis of adult rat and mouse brain membranes (Andrews et al, 2019; PMID:30667360). It has also been used in immunohistochemical analysis of KChIP3 expression in adult rat brain sections (Andrews et al, 2019; PMID:30667360) and mouse hippocampus sections (Menegola et al, 2012). Additionally, this antibody has been used to assess KChIP3 surface expression by rat primary neurons and HiB5 cells transfected to express KChIP isoforms (Pruunsild et al, 2012).
Antibody First Published
Shibata et al. A Fundamental Role for KChIPs in Determining the Molecular Properties and Trafficking of Kv4.2 Potassium Channels J Biol Chem. 2003;278(38):36445‐36454.PMID:12829703
Note on publication
Describes the original generation of this antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
